Gelatina farmacéutica

In addition to being a key ingredient in capsules, pharmaceutical gelatin is also used as a stabilizer and emulsifier in various emulsions and as a gelling agent in suspensions and ointments. Recently, it has also gained use in 3D printing to create complex layered structures, opening up new possibilities in tissue engineering. Thanks to its versatility, it is considered an innovative and multifunctional ingredient in medical devices to support healing and regeneration processes.

Gelatin capsules must meet high GMP (Good Manufacturing Practice) quality standards and ISO standards, ensuring the safety and effectiveness of the product. These requirements cover the entire production process – from the verification of the quality of raw materials to the final packaging stage – which ensures that the resulting capsules maintain stability, strength and compliance with microbiological specifications. Importantly, their solubility is also tested before they are put on the market, as this helps determine the rate at which the contents of the medicine are released in the stomach.

Pharmaceutical gelatin is distinguished by its versatility and natural origin, making it a valued ingredient in the production of medicines. Extracted from collagen contained in animal tissues, it is biologically inert and well tolerated by the body, minimizing the risk of allergic reactions. Its unique gelling properties allow the formation of durable capsules that effectively protect active substances from moisture and oxygen. Gelatin dissolves quickly at body temperature, allowing for effective medication release. In addition, by meeting high standards (GMP, ISO), pharmaceutical gelatin guarantees the safety, purity and stability of products throughout their shelf life.

Gelatin capsules, both soft and hard, are not vegan. They are made from pharmaceutical gelatin – a substance of animal origin, obtained mainly from collagen contained in pork and beef skin and bones. Those on a vegan diet should choose capsules made from alternative ingredients, such as hypromellose (HPMC) or pullulan. These substitutes offer similar gelling properties, but are entirely plant-based.

Gelatin capsules are designed to dissolve quickly in the moist environment of the digestive tract. Once ingested, the capsule begins to absorb water, leading to softening and breakdown. Under typical stomach conditions, this process takes 10 to 20 minutes, depending on the thickness of the capsule’s casing and formulation. Dissolution time can also be affected by the body’s pH and temperature, as well as the composition of the medication or dietary supplement ingested.